The rapid integration of digital technologies into daily life has fundamentally transformed how individuals access health information, manage chronic conditions, and engage in health-promoting behaviors. In the realm of mental health, digital tools—from mobile applications and wearable devices to telepsychology platforms and virtual reality—offer unprecedented opportunities for assessment, intervention, and support. However, the accelerated adoption of these technologies often outpaces rigorous research into their psychological mechanisms, long-term efficacy, and potential risks.

This Special Issue, titled “Digital Health and Psychological Well-being: Innovations, Mechanisms, and Interventions,” seeks to bridge this gap. We aim to collate cutting-edge research that critically examines the bidirectional relationship between digital health solutions and psychological outcomes. Key questions include: How do digital interventions (e.g., AI-driven chatbots, mindfulness apps, online therapy) effectively promote emotion regulation, reduce symptoms of anxiety and depression, or enhance resilience? What are the psychological and behavioral mechanisms (e.g., engagement, therapeutic alliance, self-efficacy) that underlie their success or failure? Conversely, how do aspects of the digital environment (e.g., social media design, gamification elements, data privacy concerns) influence mental well-being, body image, health behaviors, and decision-making processes?

We welcome submissions that employ diverse methodologies, including original empirical research, systematic reviews and meta-analyses, case studies, and protocol papers. Studies may focus on diverse populations across the lifespan, from adolescents navigating online well-being to adults and older adults managing chronic conditions through digital means.

Topics of interest include, but are not limited to:

• Efficacy and mechanisms of digital psychological interventions (e.g., CBT-i, mindfulness apps) for mental health.
• The role of mHealth and wearables in self-monitoring, behavior change, and treatment adherence in chronic disease management.
• Psychological impacts of social media use, online self-presentation, and digital social support.
• Design and evaluation of digital tools for stress management, emotional regulation, and psychosomatic health.
• Ethical considerations, digital equity, and personalized approaches in digital mental health.
• Integration of digital health solutions with traditional body-mind-spirit or holistic care frameworks.
• The use of novel technologies (VR, AR, AI) in exposure therapy, skills training, and enhancing motivation for physical activity and health behavior change.

By fostering a comprehensive dialogue, this Special Issue aims to advance the science of digital health psychology, guiding the development of evidence-based, ethical, and effective tools that genuinely enhance psychological well-being in the digital age.

We look forward to your contributions.